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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e4161dc329e9904d50f9a8e39cdf378ff2e226ae9dc96db200ae1684a2c16f' 
  AND token = 'jz5JV8/UG2IIzVYwsj3Pb06d0oAVkYOgjsuwwiBrcHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}