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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ce7a08d6341e6b6c4c48665515dc5011e36e0d2256654072a7646b0ef3d762' 
  AND token = 'o0VuH0r1HpbJKlcaXDVTRKkAYjEFJbsb4DnCc9jC9UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}