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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19b8656eded701368580b8d46b27bb2ecd00bd1431b36b43eef6bc3cb4e57f78' 
  AND token = 'mOw5m+6+Q5ClRp+Wvj4/9hoqXpIPw87CTpBdLgdc/MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}