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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d10a268f252ec55f2452c56c242f9844bcd030ff1c6ea5bd110bb43cea1437e' 
  AND token = 'cdmyiPC7SIZRK9Bf+YsI0/zUmg0ETXBE3m2x32DK+Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}