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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc1b0832c232bb768987c65bac2a21249913f056728bccf8bd3804b8fb960d4' 
  AND token = 'w3sRgW7XYq9dOjCAe3t3x591T3IRn37s8c8vqZqhArY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}