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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5422d2a80ca302ed1e7f9de6b9e8f13707df41d9a0e36e5a6f25bdf567b3ef' 
  AND token = 'gFgg3p18onB37NfvM6iKZMidbHI0rc0Cjl/Xmxt6LD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}