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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de15fb40961ff740c5c69ef622a75146c7eea95d59d8b9a1b4cbe4dd9153997f' 
  AND token = 'IYkvhuI30syeKsJlo3xSi2kGYSD30lDZh1L2cR6Vsgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}