SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b346ab43729b71375385902849e6b0295ba003a89ece597bdb9be400cfad2f1' 
  AND token = 'gi4usx1Pwk1wgaFonf11fm3z0eMe4+7wocGNfowuYYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}