SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd15003573da6c6159566aa94feb988d644df4aeaa9d69b8541515d21a044b50' 
  AND token = 'UVta2cO5Ctp0Yrlenu+6+Sp2lhPwC9poKWU1cpqlDQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}