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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f564a86166fdfe7161f3f4258836d6cfbd23d4ed99465e7860d93ff2b690e07' 
  AND token = 'DKRHGFpPMCCoE3A6Nv7oN+yGaRLYrcKsyW9qShKv4/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}