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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78509b94f3d49746178ca971d4681cd841e1349fdf7a69cffbf5e23784b34335' 
  AND token = '/re0Q6avXYxiFaaxLm5SPuMI6wVPEt1qAzChJ1HdflA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}