SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1014ed0de3a19026e9ca3f56d288589b54633743228a3f3282b0e60353126aaf' 
  AND token = 'fr+PqZEWyyTQ/zfcnyAl0F9bILRygXT4lf7/S8hPxc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}