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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c250e6e272018619ef6fb9dbf42b2badba506c59a45d89f75c618e11534d1e1a' 
  AND token = '2z8GH1Ioh6osBWtD+mHnowt9BIGtV6camT0t7vWi4/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}