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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8e595d998043a0f08a6a155a0d38200afa2c6fda78ec1f7bad079c24f7b0dd' 
  AND token = 'UCGHoedSZ8ahTizxQFm/nAufuER516ofcjkiAtO9zTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}