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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9d110306839380a9c6cb8130820e2b6942d74b89a65bb95e12da70f8bba0fe' 
  AND token = '+OXnupPC+OkPQSrs5dhmKhTNqf7Pxp2WfYoWRqfDmc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}