SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc84226f3a152c089d815d1ff0dcb59376ddb845d7e5eed8dd50cf93098de249' 
  AND token = 'eXC5ZDZn29zXwT0l0BTkYpNYCe1zglYXcNb4ZZUx5E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}