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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf995d9506a3093de3e6b4ea3b1cc124f4aa91a93ebcbd03125e0f9d266b9714' 
  AND token = 'EgX+RLvEne5xOQumbbhwtWs6f6F0iyBp2Bz8dFUUuvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}