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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00381113b520e02907caa03c5ef227c812d3f4dde8e5c7e3441270a55ae1ea83' 
  AND token = 'fjNd4P4PtI9hDbvHDxSaHRC/Tqny67IrkT2Uu0D2daQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}