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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4e752c4e7d027d44399ba210db9c3b5ef4ea6ea41f4121cb378a99f85fdca6' 
  AND token = 'Mrudg1cxMnfFs9BrLqD6qX37qXhA+5OhHvpy6LkrpMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}