SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5d582c05e88a51c2e29a7a480b106d0f25319d2af32f87aab2a244336ce01a' 
  AND token = 'pEoTtdzNmaBCIxg2QWuevaJPSBkGdPKg2KLf4517eHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}