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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99331c73652a1214f8cc42a21ee8b6a9c908fa1a413ce21ca2b281dbe650a3dd' 
  AND token = 'OI/npO/nK4foGKPO+nhDVFYoDKVF0L3dKtJGWGDXC/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}