SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2027df591e56efc8290bcf13136bcd11fb40d16020b84d86dbd82667a7816e0f' 
  AND token = 'd0AMML8WxNX/jYLxUQTEwdSuIfSMlvd7S/xFwlLGV10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}