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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0896809f89935e46c40f95eb6d3cdc3b8d5945d0dc88fc220938745159e90735' 
  AND token = 'LKfVs2RMfY49Oanxbnc8V+pGJgFp7kPIZjixWiehqJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}