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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb02f39d4a9f51d60a5fbb3719e3081c72d2622331c32d2206bd38b0df9da4e3' 
  AND token = '+p7E6Elc1oBSkMKiwUkLPD5ifLXX/LrHCrn0o1xKWzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}