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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27cccb5cdb3bed7b3565db8ce346a82b5eee3ca30622ff7a5e4048db5012a29' 
  AND token = 'v+lfkE7yf8RbUnnTV61MYDJXNywajmHNn31SwGLmX8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}