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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5333b33dad118b279a8bfdcd0d9953be424263aece71f79c491901a01337f0' 
  AND token = 'Z9J3OttHR/h3qg/QePUDAi+gHzRbOCrKD1Cuzuaa5cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}