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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6325b1eaf7322541a845947a7da8e9375b97ef285599bbf2b546a364effef304' 
  AND token = '44Om3NEQLyK3aMF1HLryGrGEriNSukNeceRu/ZFlzsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}