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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3acb110414cf3ca99bbdd288ec79d9ec4dd7e220d515f2ba8eaebce57e03b88d' 
  AND token = 'EAAN5QPZkvAXj4ynggU9r5pfKrcU9OfQaw4GcHMQSSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}