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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3dcdda399a4e9047e829e1bb317c7f9d13636ff960b7af0aa64b43618c7903' 
  AND token = '1o+QLd60lgBnBAeX3R/m822WNKDkkatopVRwH4tkI9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}