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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '962e544065ecc17e063be4614dcfc128ef7f64c7c0468689cc74960f98d6375f' 
  AND token = 'iUfTxvS8+fPN/No/uM0ZUtBrQgB2ds1YgG1VJGyFMlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}