SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052a6b50b8a1f13d6d23f3ece880ed051170e095fd0407df216f9b5550e28c7a' 
  AND token = 'N+qYpaDxQ41p2YEhym0txKITf6Cw1LA1nPC3UHz/5rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}