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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ddc684cc153817c538c064cff33065b1f1d0ed4b2447b0e258538520dec835' 
  AND token = 'eAqaH3W84g9C0KwWTBNNQwi0k8vmuWH62y81S7/M1p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}