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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d0a861adec759e87251fa55aa4fcdb5922ed4a0a4be6a8e93c56a1bae43f68' 
  AND token = 'iNriC5c3xpQ6Z5fUrSDuJT7e4YEhg4/mLslgw8lecc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}