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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1de17fd375c50a0defbe9406556e54e3ec00d9f1b60972a07dc4670e544ddb6' 
  AND token = 'IlOGc511ds/wWhwf826IOmp7qw7zzYsXEqBpnpStJuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}