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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22183bd3a348529d4d0f079097059e42c887f8b405ac8a58f4a65ec1d764dcc3' 
  AND token = '+s89/c3hPHzRAG24QoLZqmr4o2ShlNYxuEImFU14ejs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}