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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a71923f1d2cb50fca6d2069435986eadc8a52bed269b7e893ad7f66ca463da' 
  AND token = 'gEP2yMaAUL3tJtJ9v1MljReB+DOvJIZxMZfnhsVVMZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}