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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac1e6bcabcfde514c79562a51a138f363c5d61f469642af6b16d4e1f64865f0' 
  AND token = 'U/q3htAe8fLjUY5c/KIIsxIRH9djQ8Z4o2E30HIZnYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}