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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfac4d535f5b3b4cee892f651c50f8bb1c8da05de8d28d08b88a085789221f7' 
  AND token = 'UrtvDt4OJUjwk7f1FgZfeIzJ4aLIhLTmnp9q/DtmiqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}