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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468b1f36b55bbd1a3add96e1453bd78156c241b9ec9d7790fc2d8cc6484d454b' 
  AND token = '2pV1OsW8wFe881rLe7039NFDny1apS1pW7z5/Zy9tZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}