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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34268b9306c7f548c9cd5d00717ee1dce1a55f91927ce75627bc692e9d5257d' 
  AND token = 'la1LXIXVq42w1ZB1Z+xpfBmbnbnsc2+bhCPMeCjT7js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}