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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2964875dfd1dd2da106747d038037f20e60ecbc0f25dcfec985fa969a89a11' 
  AND token = 'AWeMEX9A3BmQHy0pA2PD4P3l0Q1+A3Xw5DsnuQVV0qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}