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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc53db0f259b8be8896c74af8c18150eaeb32593b1672f5df771351b090d2f3a' 
  AND token = 'TadY2nlVL9qDrtpSXx/7eStqBk0/UX6perL/c+eR5Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}