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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3580045d1c65ef7b5f86562ac450e37aac15154c924d1932018bf6ba21482f' 
  AND token = 'HDJcp6jAaxJp8I56pCSfYZUm6cadh4Z2VQerqJ5ZKVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}