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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4767cd4ba0660a6f76d70e232191123dc4e9bc69111a9e1356073a82080cae' 
  AND token = 'eiIV+4je9RC6LQe/hCIBwMlcX1Z4vPHKgdCoBpdlVJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}