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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5376bf9dd42924bb22435eaae175a3b1ce3bcfe5b32af89d243dca943355b8a5' 
  AND token = '+vSoWpvMlcaLe4AMRsFjLzNqF+bO+QikKaNlz2J7zt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}