SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a6547ddf7ef695e7064479547f476a27eeb6bc7da342b80db8a0fffd6fa305' 
  AND token = 'J4ep2+8Zqc5A2ETR9GUmnQ48vX4GKa5bOge5aTMT+4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}