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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4343dbed8c2481c5a609be9cca258c08121f0e339032c05c14ee37ca01e3486' 
  AND token = 'KzpGHbxPiizpSOrulFqA4rcPJRP0NXxo3jLbynRwK9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}