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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e6375e2c93b6e37e6cf864fc9e9f0348c7d0c35656cd236e64e5e1cc39bec1' 
  AND token = 'NqaHJKOWfG3KTEV23HvSlHxU9wEdvCykeDQPZlYJgcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}