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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150218e753b5b2a9b5e8ada5732f19c9c6049f849d0b8b29c71f4107b4cb3ade' 
  AND token = 'j1l3qEXZ0Mk2NknNAHQIA0GkpcxFPwFd2Yy+lxXURFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}