SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4e3fc7076f8efeda946b0647378e30555ef538d654edf5e636f0c8b39afcfd' 
  AND token = 'cG5o6Ex3YiHRGtW4XD44hnEmDoWflYaTTYh3zGkn36Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}